Psychopathology takes shape in the context of the project of reducing philosophy to anthropology. However, the medical paradigm gains ground until it becomes decisive towards the middle of the last century with the advent of the positivist perspective. Comprehensive psychopathologies, psychoanalysis, and phenomenology have corrected the clinical gaze, changed the style in telling patients’stories, and laid the foundations for a revision of relationships with others. The crisis of ethnocentrism modifies the coordinates of psychopathological observation and implies the need for an ethnoclinical mediation device, a model that encourages therapeutic practice to tighten the relationship with anthropology.